Protein co-isolated with human tissue factor impairs recovery of activity

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Protein co-isolated with human tissue factor impairs recovery of activity.

Preparations of human tissue factor isolated by immunoaffinity chromatography contain variable amounts of 47,000 mol wt, 55,000 mol wt, and multimeric tissue factor when analyzed without reduction on polyacrylamide gels in sodium dodecyl sulfate (SDS). When analyzed after reduction, the 47,000 mol wt tissue factor apoprotein and a protein of about 12,000 mol wt are observed. Elution of tissue f...

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ژورنال

عنوان ژورنال: Blood

سال: 1988

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v71.2.520.bloodjournal712520